ISSN 1662-4009 (online)

ey0015.15-14 | Memories that persist into adulthood | ESPEYB15

15.14 Epigenetic modulation of Fgf21 in the perinatal mouse liver ameliorates diet-induced obesity in adulthood

X Yuan , K Tsujimoto , K Hashimoto , K Kawahori , N Hanzawa , M Hamaguchi , T Seki , M Nawa , T Ehara , Y Kitamura

To read the full abstract: Nature Communications 2018;9:636We know that good nutrition early in life has profound and long-lasting effects on body weight in later life. Malnutrition during pregnancy or infant formula feeding may be stored on the offspring genome as epigenetic memory and persist into adulthood, thereby influencing the susceptibility to metabolic diseases, such as obes...

ey0015.15-15 | How dangerous is Bisphenol A really? | ESPEYB15

15.15 FDA Statement from Foods and Veterinary Medicine, on National Toxicology Program draft report on Bisphenol A

X Yuan , K Tsujimoto , K Hashimoto , K Kawahori , N Hanzawa , M Hamaguchi , T Seki , M Nawa , T Ehara , Y Kitamura

To read the full report: https://www.fda.gov/NewsEventsThe report, issued by the U.S. National Toxicological Program (NTP), presents the initial results of a multimillion dollar study conducted for more than 5 years by scientists at FDA’s National Center for Toxicological Research. It looked at the effects of different doses of BPA evaluating chronic and e...